UniprotKB/SwissProt ID: Q13324 (Q13324)
Gene Name:
CRHR2
Organism: Homo sapiens (Human)
Function: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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