UniprotKB/SwissProt ID: Q13253 (Q13253)
Gene Name:
NOG
Organism: Homo sapiens (Human)
Function: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (PubMed:21976273, PubMed:26643732)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted
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