Protein Name:
Peroxiredoxin-4
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UniprotKB/SwissProt ID: Q13162 (Q13162)
Gene Name:
PRDX4
Organism: Homo sapiens (Human)
Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Endoplasmic reticulum
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q13162
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
124 |
FFYPLDFTFV C PTEIIAFGDR |
CCCCCEEECC C CCCCHHHHHH |
2.77% |
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| 2 |
148 |
FRSINTEVVA C SVDSQFTHLA |
CCCCCEEECC C CCCCHHHHHH |
2.48% |
25040305
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| 3 |
245 |
FQYTDKHGEV C PAGWKPGSET |
CCCCCEEECC C CCCCHHHHHH |
1.34% |
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| 4 |
51 |
EERPRTREEE C HFYAGGQVYP |
CCCCCEEECC C CCCCHHHHHH |
2.81% |
37478858
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