Protein Name:
S-methyl-5'-thioadenosine phosphorylase
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UniprotKB/SwissProt ID: Q13126 (Q13126)
Gene Name:
MTAP
Organism: Homo sapiens (Human)
Function: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q13126
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
131 |
PQSFYDGSHS C ARGVCHIPMA |
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| 2 |
136 |
DGSHSCARGV C HIPMAEPFCP |
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| 3 |
145 |
VCHIPMAEPF C PKTREVLIET |
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| 4 |
223 |
ASIAMATDYD C WKEHEEAVSV |
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