Protein Name:
Kinesin heavy chain isoform 5A
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UniprotKB/SwissProt ID: Q12840 (Q12840)
Gene Name:
KIF5A
Organism: Homo sapiens (Human)
Function: Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Perikaryon
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q12840
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
296 |
RILQDSLGGN C RTTMFICCSP |
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| 2 |
856 |
QLVRDNADLR C ELPKLEKRLR |
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