Protein Name:
EGF-containing fibulin-like extracellular matrix protein 1
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UniprotKB/SwissProt ID: Q12805 (Q12805)
Gene Name:
EFEMP1
Organism: Homo sapiens (Human)
Function: Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q12805
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
320 |
VNEPGKFSCM C PQGYQVVRSR |
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| 2 |
338 |
RSRTCQDINE C ETTNECREDE |
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| 3 |
48 |
VRQQCKDIDE C DIVPDACKGG |
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