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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: General transcription factor 3C polypeptide 1

UniprotKB/SwissProt ID: Q12789 (Q12789)

Gene Name: GTF3C1

Organism: Homo sapiens (Human)

Function: Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR056467 eWH_GTF3C1
IPR044210 Tfc3-like
IPR035625 Tfc3-like_eWH
IPR007309 TFIIIC_Bblock-bd
IPR056428 WH_GTF3C1

The S-nitrosylation sites of Q12789

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1091 AMDKHNLERK C AMLEYTTGSR   
2 1188 WGEARVGSEL C AGWEEQFEVD   
3 1336 NPQAYLNYKV C LAEVYQDKAL   
4 136 DIRTKSLQPR C TMVEAFDRWG   
5 1363 RRGDYDDPKV C ANEFKEFVEK   
6 1520 IFTWRFPSTI C TESFQFLDRM   
7 1783 GGGRTRTFAD C IQALLEQHQV   
8 179 PDLKLPDFSY C ILERLGRSRW   
9 2046 ELLQGLESLG C IRKRWLRKPR   
10 286 LGKLREELGL C ERTFKRLYQY   
11 42 VPPFPLPLEP C TQEFLWRALA   
12 431 GRQRTTKYIS C VFAEESDLSR   
13 544 SFPGAAEERA C QSLASRDSLL   
14 853 PSSSGSAWEA C SEAPSKGSQD