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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Puromycin-sensitive aminopeptidase

UniprotKB/SwissProt ID: Q11011 (Q11011)

Gene Name: Npepps

Organism: Mus musculus (Mouse)

Function: Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR045357 Aminopeptidase_N-like_N
IPR042097 Aminopeptidase_N-like_N_sf
IPR024571 ERAP1-like_C_dom
IPR034016 M1_APN-typ
IPR001930 Peptidase_M1
IPR050344 Peptidase_M1_aminopeptidases
IPR014782 Peptidase_M1_dom
IPR027268 Peptidase_M4/M1_CTD_sf

The S-nitrosylation sites of Q11011

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 67 AEVSPINYSL C LKPDLLDFTF  CCHHHHHHHH H HHHHHHCCCC  3.64% 21278135