Protein Name:
Cleavage and polyadenylation specificity factor subunit 1
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UniprotKB/SwissProt ID: Q10570 (Q10570)
Gene Name:
CPSF1
Organism: Homo sapiens (Human)
Function: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (PubMed:14749727). May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q10570
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1020 |
PWPVRKIPLR C TAHYVAYHVE |
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| 2 |
1044 |
YAVATSTNTP C ARIPRMTGEE |
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