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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Heat shock 70 kDa protein 14

UniprotKB/SwissProt ID: Q0VDF9 (Q0VDF9)

Gene Name: HSPA14

Organism: Homo sapiens (Human)

Function: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR043129 ATPase_NBD
IPR018181 Heat_shock_70_CS
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
IPR042049 HSPA14_NBD

The S-nitrosylation sites of Q0VDF9

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 280 HSLSTLGSAN C FLDSLYEGQD   
2 335 TADDINKVVL C GGSSRIPKLQ   
3 492 MKRDGSLHVT C TDQETGKCEA   
4 500 VTCTDQETGK C EAISIEIAS-   
5 89 QAQKYIAESK C LVIEKNGKLR