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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: NADPH-dependent aldo-keto reductase, chloroplastic

UniprotKB/SwissProt ID: Q0PGJ6 (Q0PGJ6)

Gene Name: AKR4C9

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Oxidoreductase acting on a broad range of substrates: reduces ketosteroids, aromatic aldehydes, ketones, sugars and other aliphatic aldehydes, and oxidizes hydroxysteroids (PubMed:19616008). Aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes (PubMed:21169366). No activity on alpha,beta-unsaturated ketones (PubMed:21169366). Can use propionaldehyde, butyraldehyde, methylglyoxal, (E)-2-pentenal, (E)-2-hexenal, (Z)-3-hexenal and (E)-2-nonenal as substrates, propenal (acrolein), crotonaldehyde, but not 2-butanone, 3-buten-2-one or 1-penten-3-one (PubMed:21169366). May function as detoxifiying enzyme by reducing a range of toxic aldehydes and ketones produced during stress (PubMed:19616008)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Plastid, chloroplast

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR020471 AKR
IPR044498 AKR4C
IPR018170 Aldo/ket_reductase_CS
IPR023210 NADP_OxRdtase_dom
IPR036812 NADP_OxRdtase_dom_sf