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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein mesh

UniprotKB/SwissProt ID: Q0KHY3 (Q0KHY3)

Gene Name: mesh

Organism: Drosophila melanogaster (Fruit fly)

Function: Required, together with Ssk and Tsp2A, for the proper organization of smooth septate junctions (sSJs), probably by mediating cell adhesion via its homophilic interaction (PubMed:22854041, PubMed:26848177). Also required for the correct subcellular localization of several sSJ components, such as Ssk, cora and l(2)gl, and for the barrier function of the midgut epithelium (PubMed:22854041). Required for maintaining the three-layered structure of the proventriculus (PubMed:22854041)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell junction, septate junction. Apicolateral cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR005533 AMOP_dom
IPR056619 C8-3_MUC4
IPR051495 Epithelial_Barrier/Signaling
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR003886 NIDO_dom
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
IPR001846 VWF_type-D