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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Desmocollin-1

UniprotKB/SwissProt ID: Q08554 (Q08554)

Gene Name: DSC1

Organism: Homo sapiens (Human)

Function: A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion (By similarity). Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation (By similarity). Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Cell junction, desmosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050971 Cadherin-domain_protein
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR014868 Cadherin_pro_dom
IPR027397 Catenin-bd_sf
IPR009122 Desmosomal_cadherin

The S-nitrosylation sites of Q08554

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 417 TDPNTNEGVL C VVKPLNYEVN