Protein Name:
RNA-binding protein squid
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UniprotKB/SwissProt ID: Q08473 (Q08473)
Gene Name:
sqd
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of ribonucleosomes (PubMed:7684991). Could be needed to organize a concentration gradient of a dorsalizing morphogen (Dm) originating in the germinal vesicle (PubMed:7684991). At least one of the isoforms is essential in somatic tissues (PubMed:7684991). Interacts with grk mRNA (via 3' UTR) and involved in its localization to the dorsal anterior region of the oocyte during dorsal-ventral axis determination; may function as a ribonuclear protein complex together with otu and Hrb27C (PubMed:10197986, PubMed:15056611). Required for polytene chromosome dispersal in nurse cells during oogenesis; nuclear isoforms play a greater role in this than cytoplasmic isoforms (PubMed:15056611) Required nonredundantly with isoform A/sqdA for dorsoventral pattern determination during oogenesis (PubMed:10197986). May be important in somatic tissues (PubMed:10197986, PubMed:7684991) Required nonredundantly with isoform B/SqdS for dorsoventral pattern determination during oogenesis May lack a role in dorsoventral pattern determination during oogenesis (PubMed:10197986). May be important in somatic tissues (PubMed:10197986)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Nucleus. Cytoplasm. Cytoplasm. Nucleus. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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