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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

UniprotKB/SwissProt ID: Q07098 (Q07098)

Gene Name: PP2A2

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Dephosphorylates and activates the actin-depolymerizing factor ADF1, which, in turn, regulates actin cytoskeleton remodeling and is involved in the blue light photoreceptor PHOT2-mediated chloroplast avoidance movements (PubMed:22642987). Associates with the serine/threonine-protein phosphatase PP2A regulatory subunits A and B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins (PubMed:25489022). Acts as a negative regulator of abscisic acid (ABA) signaling. May regulate ABA-dependent gene expression (PubMed:17617176). Involved in the light-dependent activation of nitrate reductase (PubMed:28656346)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus. Peroxisome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR047129 PPA2-like
IPR006186 Ser/Thr-sp_prot-phosphatase

The S-nitrosylation sites of Q07098

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 193 IQEVPHEGPM C DLLWSDPDDR