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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: GA-binding protein alpha chain

UniprotKB/SwissProt ID: Q06546 (Q06546)

Gene Name: GABPA

Organism: Homo sapiens (Human)

Function: Transcription factor capable of interacting with purine rich repeats (GA repeats). Positively regulates transcription of transcriptional repressor RHIT/ZNF205 (PubMed:22306510) (Microbial infection) Necessary for the expression of the Adenovirus E4 gene

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000418 Ets_dom
IPR046328 ETS_fam
IPR024668 GABP_asu_N
IPR003118 Pointed_dom
IPR013761 SAM/pointed_sf
IPR016312 TF_GA-bd_asu
IPR029071 Ubiquitin-like_domsf
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf

The S-nitrosylation sites of Q06546

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 223 TTLNISGREL C SLNQEDFFQR   
2 37 IVEQTYAPAE C VSQAIDINEP   
3 388 LRYYYDGDMI C KVQGKRFVYK   
4 69 LQCSLDAHEI C LQDIQLDPER