Protein Name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
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UniprotKB/SwissProt ID: Q06210 (Q06210)
Gene Name:
GFPT1
Organism: Homo sapiens (Human)
Function: Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1 (By similarity). Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling (PubMed:26887390)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q06210
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
2 |
---------M C GIFAYLNYHV |
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37478858
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| 2 |
254 |
GERGKDKKGS C NLSRVDSTTC |
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| 3 |
264 |
CNLSRVDSTT C LFPVEEKAVE |
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| 4 |
392 |
QRCRRLILIA C GTSYHAGVAT |
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37478858
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| 5 |
435 |
RNTPVFRDDV C FFLSQSGETA |
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| 6 |
478 |
VGSSISRETD C GVHINAGPEI |
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| 7 |
55 |
GNDKDWEANA C KIQLIKKKGK |
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| 8 |
570 |
IMGRGYHYAT C LEGALKIKEI |
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| 9 |
638 |
VARQGRPVVI C DKEDTETIKN |
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