Protein Name:
Lactoylglutathione lyase
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UniprotKB/SwissProt ID: Q04760 (Q04760)
Gene Name:
GLO1
Organism: Homo sapiens (Human)
Function: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294). Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (PubMed:19199007). Required for normal osteoclastogenesis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q04760
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
139 |
GIAVPDVYSA C KRFEELGVKF |
CCCCCCCCCC C CHHHHHHHCC |
2.39% |
25040305
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| 2 |
61 |
RVLGMTLIQK C DFPIMKFSLY |
CCCCCCCCCC C CHHHHHHHCC |
3.6% |
19483679
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