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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 1,4-alpha-glucan-branching enzyme

UniprotKB/SwissProt ID: Q04446 (Q04446)

Gene Name: GBE1

Organism: Homo sapiens (Human)

Function: Glycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen synthase. Generates alpha-1,6-glucosidic branches from alpha-1,4-linked glucose chains, to increase solubility of the glycogen polymer (PubMed:26199317, PubMed:8463281, PubMed:8613547)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set

The S-nitrosylation sites of Q04446

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 221 GKVASYKHFT C NVLPRIKGLG  CCCCCCCCCC H HHHHHHHHHH  3.03%
2 309 GLNMFDGTDS C YFHSGPRGTH  CCCCCCCCCC H HHHHHHHHHH  4.72%
3 473 TLTNRRYLEK C IAYAESHDQA  CCCCCCCCCC H HHHHHHHHHH  1.25%
4 81 RGYESFGVHR C ADGGLYCKEW  CCCCCCCCCC H HHHHHHHHHH  2.15% 2212679
5 88 VHRCADGGLY C KEWAPGAEGV  CCCCCCCCCC H HHHHHHHHHH  3.76% 2212679