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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Mevalonate kinase

UniprotKB/SwissProt ID: Q03426 (Q03426)

Gene Name: MVK

Organism: Homo sapiens (Human)

Function: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis (PubMed:11278915, PubMed:18302342, PubMed:9325256, PubMed:9392419)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Peroxisome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013750 GHMP_kinase_C_dom
IPR036554 GHMP_kinase_C_sf
IPR006204 GHMP_kinase_N_dom
IPR006203 GHMP_knse_ATP-bd_CS
IPR006205 Mev_gal_kin
IPR020568 Ribosomal_Su5_D2-typ_SF
IPR014721 Ribsml_uS5_D2-typ_fold_subgr

The S-nitrosylation sites of Q03426

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 275 LTSIDAISLE C ERVLGEMGEA