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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Mitochondrial-processing peptidase subunit beta

UniprotKB/SwissProt ID: Q03346 (Q03346)

Gene Name: Pmpcb

Organism: Rattus norvegicus (Rat)

Function: Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable) (PubMed:12433926). Preferentially, cleaves after an arginine at position P2 (PubMed:12433926). Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis (PubMed:22354088)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011249 Metalloenz_LuxS/M16
IPR050361 MPP/UQCRC_Complex
IPR011765 Pept_M16_N
IPR001431 Pept_M16_Zn_BS
IPR007863 Peptidase_M16_C

The S-nitrosylation sites of Q03346

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 419 LLQLDGSTPI C EDIGRQMLCY