Protein Name:
ATP synthase F(1) complex subunit alpha, mitochondrial
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UniprotKB/SwissProt ID: Q03265 (Q03265)
Gene Name:
Atp5f1a
Organism: Mus musculus (Mouse)
Function: Subunit alpha, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). With the catalytic subunit beta (ATP5F1B), forms the catalytic core in the F(1) domain. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q03265
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
244 |
DGTDEKKKLY C IYVAIGQKRS |
CCHHHHHHHH H HHCHHHHCCC |
2.34% |
22178444
21278135
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| 2 |
294 |
PLQYLAPYSG C SMGEYFRDNG |
CCHHHHHHHH H HHCHHHHCCC |
1.76% |
21278135
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