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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Transcription factor Sp3

UniprotKB/SwissProt ID: Q02447 (Q02447)

Gene Name: SP3

Organism: Homo sapiens (Human)

Function: Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Nucleus, PML body

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

The S-nitrosylation sites of Q02447

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 602 GKRLRRVACT C PNCKEGGGRG