UniprotKB/SwissProt ID: Q01955 (Q01955)
Gene Name:
COL4A3
Organism: Homo sapiens (Human)
Function: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane
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