UniprotKB/SwissProt ID: Q01726 (Q01726)
Gene Name:
MC1R
Organism: Homo sapiens (Human)
Function: Receptor for MSH (alpha, beta and gamma) and ACTH (PubMed:11442765, PubMed:11707265, PubMed:1325670, PubMed:1516719, PubMed:8463333). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11707265, PubMed:1325670, PubMed:16463023, PubMed:19737927). Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes (PubMed:31097585)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
|
|
|
