Protein Name:
3-hydroxy-3-methylglutaryl-coenzyme A reductase
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UniprotKB/SwissProt ID: Q01237 (Q01237)
Gene Name:
Hmgcr
Organism: Mus musculus (Mouse)
Function: Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Peroxisome membrane
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Graphical Visualization of S-nitrosylation Sites:
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