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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Spectrin beta chain, non-erythrocytic 1

UniprotKB/SwissProt ID: Q01082 (Q01082)

Gene Name: SPTBN1

Organism: Homo sapiens (Human)

Function: Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Plays a critical role in central nervous system development and function

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, cytosol. Cell membrane. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001589 Actinin_actin-bd_CS
IPR001715 CH_dom
IPR036872 CH_dom_sf
IPR011993 PH-like_dom_sf
IPR041681 PH_9
IPR001605 PH_dom-spectrin-type
IPR001849 PH_domain
IPR018159 Spectrin/alpha-actinin
IPR016343 Spectrin_bsu
IPR002017 Spectrin_repeat

The S-nitrosylation sites of Q01082

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 112 KPTKGRMRIH C LENVDKALQF   
2 1284 NRDLQKFLQD C QELSLWINEK   
3 1900 LEAWKSLLDA C ESRRVRLVDT   
4 604 FATDGEGYKP C DPQVIRDRVA   
5 619 IRDRVAHMEF C YQELCQLAAE   
6 964 ALSIQNYHLE C NETKSWIREK