Protein Name:
Ubiquitin carboxyl-terminal hydrolase isozyme L1
|
UniprotKB/SwissProt ID: Q00981 (Q00981)
Gene Name:
Uchl1
Organism: Rattus norvegicus (Rat)
Function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (By similarity). This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (By similarity). Also binds to free monoubiquitin and may prevent its degradation in lysosomes (By similarity). The homodimer may have ATP-independent ubiquitin ligase activity (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Endoplasmic reticulum membrane
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of Q00981
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
152 |
AHDSVAQEGQ C RVDDKVNFHF |
CCCCCCCCCH H HHHHHHHHHC |
7.23% |
22178444
16418269
21278135
|
| 2 |
220 |
GEVRFSAVAL C KAA------- |
CCCCCCCCCH H HHHHHHHHHC |
1.71% |
21278135
|
|
