UniprotKB/SwissProt ID: Q00174 (Q00174)
Gene Name:
LanA
Organism: Drosophila melanogaster (Fruit fly)
Function: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Activates presynaptic signaling involving integrin alpha-PS3/beta-nu and Fak to suppress neuromuscular junction (NMJ) growth during larval development and during low crawling activity, but not during higher-crawling conditions. Mediates, together with integrin alpha-PS3/beta-nu, glutamate receptor-modulated NMJ growth
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane. Synapse. Cell projection, axon. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle
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