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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Phosphatidylinositol transfer protein alpha isoform

UniprotKB/SwissProt ID: Q00169 (Q00169)

Gene Name: PITPNA

Organism: Homo sapiens (Human)

Function: Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:10531358, PubMed:14962392, PubMed:15522822, PubMed:18636990, PubMed:22822086). Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions (PubMed:15522822, PubMed:22822086). Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3 (PubMed:22822086)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001666 PI_transfer
IPR055261 PI_transfer_N
IPR023393 START-like_dom_sf

The S-nitrosylation sites of Q00169

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 187 WKQELVNQKD C PYMCAYKLVT   
2 94 HEKAWNAYPY C RTVITNEYMK