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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Peroxiredoxin-5, mitochondrial

UniprotKB/SwissProt ID: P99029 (P99029)

Gene Name: Prdx5

Organism: Mus musculus (Mouse)

Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion. Cytoplasm. Peroxisome matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR037944 PRX5-like
IPR013740 Redoxin
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain

The S-nitrosylation sites of P99029

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 200 NVEPDGTGLT C SLAPNILSQL  CCCHHHHHHC C CHHHHHHHHH  3.64% 24895380
22588120
21278135
2 96 FGVPGAFTPG C SKTHLPGFVE  CCCHHHHHHC C CHHHHHHHHH  3.87% 24895380
22588120
21278135