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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tubulin beta-5 chain
UniprotKB/SwissProt ID: P99024 (P99024)

Gene Name: Tubb5

Organism: Mus musculus (Mouse)

Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013838 Beta-tubulin_BS
IPR002453 Beta_tubulin
IPR008280 Tub_FtsZ_C
IPR000217 Tubulin
IPR037103 Tubulin/FtsZ-like_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR023123 Tubulin_C
IPR017975 Tubulin_CS
IPR003008 Tubulin_FtsZ_GTPase
The S-nitrosylation sites of P99024
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 12 REIVHIQAGQ C GNQIGAKFWE  CCEEEEEECC C CCCCHHHHHH  5.6% 24926564
22588120
20925432
2 127 LDVVRKEAES C DCLQGFQLTH  CCEEEEEECC C CCCCHHHHHH  3.01%
3 239 VSATMSGVTT C LRFPGQLNAD  CCEEEEEECC C CCCCHHHHHH  1.55% 20925432
4 303 VFDAKNMMAA C DPRHGRYLTV  CCEEEEEECC C CCCCHHHHHH  5.55% 24926564
5 354 WIPNNVKTAV C DIPPRGLKMA  CCEEEEEECC C CCCCHHHHHH  3.49% 24926564
22588120