Protein Name:
FXYD domain-containing ion transport regulator 5
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UniprotKB/SwissProt ID: P97808 (P97808)
Gene Name:
Fxyd5
Organism: Mus musculus (Mouse)
Function: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane (PubMed:16148001, PubMed:17881459). May increase NKA activity by increasing the apparent affinity for Na(+) (PubMed:17881459). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Basolateral cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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