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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: tRNA (guanine(6)-N(2))-methyltransferase THUMP3

UniprotKB/SwissProt ID: P97770 (P97770)

Gene Name: Thumpd3

Organism: Mus musculus (Mouse)

Function: Catalytic subunit of the THUMPD3-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 6 (m2G6) in tRNAs. This is one of the major tRNA (guanine-N(2))-methyltransferases. Also catalyzes the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 7 of tRNA(Trp)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000241 RlmKL-like_Mtase
IPR053943 RlmKL-like_Mtase_CS
IPR029063 SAM-dependent_MTases_sf
IPR004114 THUMP_dom