Protein Name:
Dihydropyrimidinase-related protein 1
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UniprotKB/SwissProt ID: P97427 (P97427)
Gene Name:
Crmp1
Organism: Mus musculus (Mouse)
Function: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (PubMed:14685275, PubMed:25358863). Plays a role in axon guidance (PubMed:14685275). During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone (PubMed:25358863). Involved in invasive growth and cell migration (By similarity). May participate in cytokinesis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cell projection, growth cone. Cytoplasm, cytoskeleton. Perikaryon
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P97427
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
248 |
RAIAIAGRIN C PVYITKVMSK |
CCCCCCCCCC C CCCCCEEEEC |
1.93% |
22588120
19101475
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| 2 |
439 |
VEYNIFEGME C HGSPLVVISQ |
CCCCCCCCCC C CCCCCEEEEC |
3.06% |
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