Protein Name:
Neuroplastin
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UniprotKB/SwissProt ID: P97300 (P97300)
Gene Name:
Nptn
Organism: Mus musculus (Mouse)
Function: Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity (By similarity). Also acts as a chaperone for ATP2B1; stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Postsynaptic density
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P97300
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
116 |
LTLEDSGTYE C RASNDPKRND |
CCCCCHHHHH H HHHHHHHCCC |
2.87% |
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| 2 |
217 |
PRAEDSGEYH C VYHFVSAPKA |
CCCCCHHHHH H HHHHHHHCCC |
2.96% |
24895380
22588120
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| 3 |
258 |
KNEGQDAMMY C KSVGYPHPEW |
CCCCCHHHHH H HHHHHHHCCC |
1.12% |
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