UniprotKB/SwissProt ID: P92177 (P92177)
Gene Name:
14-3-3epsilon
Organism: Drosophila melanogaster (Fruit fly)
Function: Positively regulates Ras-mediated pathways. Acts downstream or parallel to Raf, but upstream of nuclear factors in Ras signaling. Three mutants have been isolated, that suppress the rough eye phenotype caused by mutated Ras1 (sev-Ras1 v12). Inhibits yki activity by restricting its nuclear localization. Together with pav, has a role in the inhibition of microtubule sliding during neurite outgrowth (PubMed:32022690)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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