UniprotKB/SwissProt ID: P85845 (P85845)
Gene Name:
Fscn1
Organism: Rattus norvegicus (Rat)
Function: Actin-binding protein that contains 2 major actin binding sites (PubMed:8769857). Organizes filamentous actin into parallel bundles (PubMed:8769857). Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cell projection, growth cone. Cell projection, filopodium. Cell projection, invadopodium. Cell projection, microvillus. Cell junction
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