Protein Name:
Elongation factor Tu, mitochondrial
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UniprotKB/SwissProt ID: P85834 (P85834)
Gene Name:
Tufm
Organism: Rattus norvegicus (Rat)
Function: GTP hydrolase that promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIGI-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P85834
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
127 |
TAARHYAHTD C PGHADYVKNM |
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| 2 |
290 |
ERGILKKGDE C ELLGHNKNIR |
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