Protein Name:
Rho-related GTP-binding protein RhoG
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UniprotKB/SwissProt ID: P84096 (P84096)
Gene Name:
Rhog
Organism: Mus musculus (Mouse)
Function: Plays a role in immunological synaptic F-actin density and architecture organization (By similarity). Regulates actin reorganization in lymphocytes, possibly through the modulation of Rac1 activity (By similarity). Required for the formation of membrane ruffles during macropinocytosis (By similarity). Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes (By similarity). Binds phospholipids in an activation-dependent manner; thereby acting as an anchor for other proteins to the plasma membrane (PM) (By similarity). Plays a role in exocytosis of cytotoxic granules (CG) by lymphocytes/Component of the exocytosis machinery in natural killer (NK) and CD8+ T cells (By similarity). Promotes the docking of cytotoxic granules (CG) to the plasma membrane through the interaction with UNC13D (By similarity). Involved in the cytotoxic activity of lymphocytes/primary CD8+ T cells (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P84096
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
105 |
HKWHPEVCHH C PDVPILLVGT |
CCCCEEEEEC C CCCCCEEEEE |
1.05% |
20925432
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| 2 |
157 |
KQIHAVRYLE C SALQQDGVKE |
CCCCEEEEEC C CCCCCEEEEE |
2.38% |
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| 3 |
18 |
VVGDGAVGKT C LLICYTTNAF |
CCCCEEEEEC C CCCCCEEEEE |
3.11% |
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| 4 |
6 |
-----MQSIK C VVVGDGAVGK |
CCCCEEEEEC C CCCCCEEEEE |
2.4% |
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