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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Galectin-1

UniprotKB/SwissProt ID: P81184 (P81184)

Gene Name: LGALS1

Organism: Ovis aries (Sheep)

Function: Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation (PubMed:9546655). Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity). Strong inducer of T-cell apoptosis (PubMed:9546655)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix. Cytoplasm. Secreted

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013320 ConA-like_dom_sf
IPR044156 Galectin-like
IPR001079 Galectin_CRD

The S-nitrosylation sites of P81184

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 17 ASNLNLKPGE C LRVRGEVAAD   
2 43 LNLGKDDNNL C LHFNPRFNAH   
3 61 NAHGDINTIV C NSKDGGAWGA