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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: C-C motif chemokine 8

UniprotKB/SwissProt ID: P80075 (P80075)

Gene Name: CCL8

Organism: Homo sapiens (Human)

Function: Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR039809 Chemokine_b/g/d
IPR000827 Chemokine_CC_CS
IPR001811 Chemokine_IL8-like_dom
IPR036048 Interleukin_8-like_sf