Protein Name:
Dipeptidyl peptidase 1
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UniprotKB/SwissProt ID: P80067 (P80067)
Gene Name:
Ctsc
Organism: Rattus norvegicus (Rat)
Function: Thiol protease (PubMed:1740150). Has dipeptidylpeptidase activity (PubMed:1740150). Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate (PubMed:1740150). Can act as both an exopeptidase and endopeptidase (By similarity). Activates serine proteases such as elastase, cathepsin G and granzymes A and B (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Lysosome
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Graphical Visualization of S-nitrosylation Sites:
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