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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: CTP synthase 1

UniprotKB/SwissProt ID: P70698 (P70698)

Gene Name: Ctps1

Organism: Mus musculus (Mouse)

Function: This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR029062 Class_I_gatase-like
IPR004468 CTP_synthase
IPR017456 CTP_synthase_N
IPR017926 GATASE
IPR033828 GATase1_CTP_Synthase
IPR027417 P-loop_NTPase

The S-nitrosylation sites of P70698

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 216 GLGLSPDLVV C RCSNPLDTSV  CCEEEEECCC C CCCCCCHHHH  2.57% 20925432
2 218 GLSPDLVVCR C SNPLDTSVKE  CCEEEEECCC C CCCCCCHHHH  3.79%
3 30 ASSVGTILKS C GLHVTSIKID  CCEEEEECCC C CCCCCCHHHH  6.85% 20925432
4 362 VRYHEAWQKL C SAHGVLVPGG  CCEEEEECCC C CCCCCCHHHH  4.32%