UniprotKB/SwissProt ID: P70694 (P70694)
Gene Name:
Akr1c6
Organism: Mus musculus (Mouse)
Function: Active toward androgens, estrogens, and xenobiotic substrates. Also exhibits low 20 alpha-HSD activity. Shows a-stereospecificity in hydrogen transfer between cofactors and substrates (A-specific). Preferentially catalyzes the reduction of 4-androstenedione, 5-alpha-androstane-3,17-dione, androsterone and dehydroepiandrosterone to testosterone, dihydrotestosterone, 5-alpha-androstane-3-alpha,17-beta-diol and 5-androstene-3-beta,17-beta-diol, respectively
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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