Protein Name:
Lactadherin
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UniprotKB/SwissProt ID: P70490 (P70490)
Gene Name:
Mfge8
Organism: Rattus norvegicus (Rat)
Function: Contributes to phagocytic removal of apoptotic cells in many tissues. Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Appears to participate in the O-acetylation of GD3 ganglioside sialic acid
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane. Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P70490
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
254 |
AQYIRLYPVS C HRGCTLRFEL |
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