Protein Name:
Vasodilator-stimulated phosphoprotein
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UniprotKB/SwissProt ID: P70460 (P70460)
Gene Name:
Vasp
Organism: Mus musculus (Mouse)
Function: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell junction, tight junction. Cell projection, lamellipodium membrane. Cell projection, filopodium membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P70460
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
332 |
TTSEAHPSTP C SSDDSDLERV |
CCCEEEECCC C EEEEEECCCC |
6.52% |
21278135
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| 2 |
64 |
MQPDQQVVIN C AIIRGVKYNQ |
CCCEEEECCC C EEEEEECCCC |
1.66% |
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