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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: TNF receptor-associated factor 5

UniprotKB/SwissProt ID: P70191 (P70191)

Gene Name: Traf5

Organism: Mus musculus (Mouse)

Function: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002083 MATH/TRAF_dom
IPR012227 TNF_rcpt-assoc_TRAF_met
IPR008974 TRAF-like
IPR049342 TRAF1-6_MATH_dom
IPR049440 TRAF3/5_RING
IPR027130 TRAF5_C3HC3D_RING-HC_finger
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
IPR001293 Znf_TRAF