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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Hemoglobin subunit alpha

UniprotKB/SwissProt ID: P69905 (P69905)

Gene Name: HBA1

Organism: Homo sapiens (Human)

Function: Involved in oxygen transport from the lung to the various peripheral tissues Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 (PubMed:18077343). Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling (PubMed:18077343)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002338 Hemoglobin_a-typ
IPR050056 Hemoglobin_oxygen_transport
IPR002339 Hemoglobin_pi

The S-nitrosylation sites of P69905

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 105 DPVNFKLLSH C LLVTLAAHLP  CCCCHHHCCC C HHHHHHCCHH  2.56% 22178444
17350155