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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: E3 ubiquitin-protein ligase PDZRN3

UniprotKB/SwissProt ID: P68907 (P68907)

Gene Name: Pdzrn3

Organism: Rattus norvegicus (Rat)

Function: E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Synapse. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR051971 E3_ubiquitin-PDZ_ligase
IPR001478 PDZ
IPR036034 PDZ_sf
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
IPR001293 Znf_TRAF

The S-nitrosylation sites of P68907

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 764 SSSAYNTGES C RSTPLTLEIS